"/>

国产精品99一区二区三_免费中文日韩_国产在线精品一区二区_日本成人手机在线

Hormone points to better lung cancer chemotherapy treatment: Aussie research
Source: Xinhua   2018-07-26 12:24:16

SYDNEY, July 26 (Xinhua) -- A naturally occurring hormone could help make chemotherapy much more effective for many lung cancer patients, at the same time helping them avoid a kidney damage side effect from the usual treatment, according to Australian research findings released on Thursday.

When Professor Neil Watkins from the Garvan Institute for Medical Research and his team discovered that the protein activin was behind chemotherapy resistance and chemotherapy- induced kidney damage, it led them to develop the naturally occurring hormone follistatin - which blocks activin - to specifically treat inflammatory and fibrotic diseases.

Their lab tests on mice found that treatment of follistatin in combination with platinum- based chemotherapy caused lung tumors to shrink and more animals to survive longer, with kidney damage also prevented, the institute said in a statement.

"Because follistatin is a hormone already found in the human body, there is much less potential for toxicity than with other drugs used to reduce chemoresistance," said Watkins.

Research team member Kieren Marini said "discoveries like this one - a combination therapy that actually reduces damage while improving effectiveness of chemotherapy - are exceedingly rare in cancer research."

Their findings, published in the Science Translational Medicine medical journal, have laid the foundations to move this "combination therapy," of reducing damage while improving effectiveness of chemotherapy, to a clinical setting.

There are also plans to study other tumors where platinum chemotherapy is commonly used, such as bladder and head and neck cancers, said Watkins.

Editor: Liangyu
Related News
Xinhuanet

Hormone points to better lung cancer chemotherapy treatment: Aussie research

Source: Xinhua 2018-07-26 12:24:16
[Editor: huaxia]

SYDNEY, July 26 (Xinhua) -- A naturally occurring hormone could help make chemotherapy much more effective for many lung cancer patients, at the same time helping them avoid a kidney damage side effect from the usual treatment, according to Australian research findings released on Thursday.

When Professor Neil Watkins from the Garvan Institute for Medical Research and his team discovered that the protein activin was behind chemotherapy resistance and chemotherapy- induced kidney damage, it led them to develop the naturally occurring hormone follistatin - which blocks activin - to specifically treat inflammatory and fibrotic diseases.

Their lab tests on mice found that treatment of follistatin in combination with platinum- based chemotherapy caused lung tumors to shrink and more animals to survive longer, with kidney damage also prevented, the institute said in a statement.

"Because follistatin is a hormone already found in the human body, there is much less potential for toxicity than with other drugs used to reduce chemoresistance," said Watkins.

Research team member Kieren Marini said "discoveries like this one - a combination therapy that actually reduces damage while improving effectiveness of chemotherapy - are exceedingly rare in cancer research."

Their findings, published in the Science Translational Medicine medical journal, have laid the foundations to move this "combination therapy," of reducing damage while improving effectiveness of chemotherapy, to a clinical setting.

There are also plans to study other tumors where platinum chemotherapy is commonly used, such as bladder and head and neck cancers, said Watkins.

[Editor: huaxia]
010020070750000000000000011100001373494191
主站蜘蛛池模板: 徐水县| 贵南县| 阿拉善盟| 文安县| 稻城县| 瓦房店市| 兴国县| 嘉祥县| 南平市| 宁国市| 抚顺县| 石嘴山市| 宁强县| 上杭县| 鄂伦春自治旗| 洛南县| 兴化市| 赞皇县| 聊城市| 前郭尔| 东平县| 东阳市| 泰安市| 鄄城县| 定远县| 英德市| 林西县| 石家庄市| 清徐县| 吴堡县| 龙川县| 子洲县| 汕头市| 大田县| 华安县| 龙里县| 阳山县| 临潭县| 六枝特区| 大宁县| 岐山县|